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Consequently, increased reactive oxygen species levels lead to decreased levels of reduced GSH and increased levels of TGF-, which has been demonstrated to inhibit the rate-limiting enzyme responsible for the de novo synthesis of GSH
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The red cells rarely disintegrate in the circulation, so hemoglobin is rarely excreted directly by the kidney, but this can occur in severe cases, causing acute kidney injury
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Medicines in this drug class stimulate the pancreas to produce more insulin which improves the uptake of glucose from food
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