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Emerging evidence from human and animal studies of neurological diseases indicates that BBB disruption is associated with changes in BM component synthesis and degradation [64]
10.1007/s00018-022-04288-0 17 FlorouP.AnagnostisP.TheocharisP.ChourdakisM.GoulisD
In contrast, rats treated with metformin did not display this aberrant enrichment in Galactose metabolism and Primary bile acid biosynthesis, indicating that metformin may exert a regulatory effect on these specific metabolic pathways, potentially aiding in the restoration of normal metabolic function or at least mitigating metabolic dysregulation
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10.1002/JBT.22368 42 JiaD.LiZ
