liraglutide (Saxenda, Victoza) is older and generally milder
Multiple pages suggest subcutaneous injection is equivalent to intranasal or IV because "that is how research peptides are typically dosed." DSIP's rapid plasma degradation makes route a primary pharmacokinetic variable, not an administrative detail
doi:10.1056/NEJMoa1607141 Rodbard HW, Rosenstock J, Canani LH, et al
ATTAIN-1 (NCT05869903) The key trial for the obesity indication, ATTAIN-1 randomized 3,127 adults with obesity or overweight (without diabetes) to orforglipron 6 mg, 12 mg, or 36 mg versus placebo for 72 weeks
Vogel H, Mirhashemi F, Liehl B et al (2013) Estrogen deficiency aggravates insulin resistance and induces -cell loss and diabetes in female new Zealand obese mice
If you're considering GLP-1 medications for your child, the most important step is to have an open, honest conversation with a qualified healthcare provider who can evaluate your child's individual situation, discuss the potential benefits and risks and help develop a personalized treatment plan
