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[4] [5] By activating GLP-1 receptors, retatrutide is thought to enhance insulin secretion in a glucose-dependent manner, suppress glucagon release, and reduce appetite by acting on satiety centres in the brain

Patients should discuss any questions or concerns about their medication with their healthcare provider

This blog will deep dive into this topic, explaining how each medication works, their overlap as GLP-1 receptor agonists, and why combining them is not recommended