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( F ) Quantification of exogenous palmitic acid oxidation measured in caSMCs that were pretreated with 100 nM GLP-1(2836) or scrambled control for 20 minutes

Positive measurement bias ranged from 0.01 to 0.54 for 41% of the sample and was predominantly explained by healthcare utilization, demographics and social needs (d = 30%, 29%, 29%, respectively

When assessing TH1- and TH2-related cytokines separately, we observed that females had higher levels of TH2-related cytokines than males (main effect of sex for TH2: F (1,55) = 4.615, R 2 = 0.083, p = 0.018), but not TH1-related cytokines, nor were there any other significant main effects or interactions present, although there was a trend towards a diet effect (main effect of diet: p = 0.060

The peptide was reportedly investigated for mild-to-moderate ulcerative colitis with no major safety concerns reported