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Methods Enzymol 113:484490
Concierge Medical Boutique for bespoke healthcare journeys
Updated 7-31-23, 11:10 am EDT: This story was updated to correct Thorne's berberine sales figures.
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
Curated data place Melanotan 1 as a full agonist at four subtypes with a clear order-of-magnitude preference for MC1R: pIC 10.0 at MC1R, pKi 8.9 at MC3R, pKi 8.5 to 8.8 at MC4R, pIC 9.0 at MC5R, and no activity at MC2R
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