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For many patients, a surgical option like a gastric sleeve would likely provide much better long-term weight loss results at a much lower cost and side-effect profile

Furthermore, the activation of NADPH oxidases, particularly NOX4, has been identified as a significant source of ROS in diabetic contexts, thereby intensifying oxidative damage to neural tissues (Syed et al., 2023)

The purpose of this review is to provide an overview of key studies that have afforded insight into how intestinal immune function, inflammation and barrier function impact on the development of obesity and T2D with specific focus on immune function and intestinal epithelial cells

Weight regain is possible if medication is discontinued abruptly without sustainable lifestyle changes in place

One important note

This is not a fad nor diet