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Some researchers report visible improvements in skin texture and hydration within 46 weeks

All procedures were conducted in compliance with IACUC-approved protocols at City of Hope animal facilities (IACUC #22043)

Use aseptic technique, rotate sites to prevent soreness, and use an appropriate needle (e.g

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These include immune checkpoint inhibitors (ICIs) targeting PD-1/PD-L1, such as pembrolizumab and nivolumab, which have exhibited encouraging results in early clinical trials [146, 147]