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Rotate injection sites each week to reduce irritation and lower the risk of lipohypertrophy (fatty lumps), even though the risk is relatively low with once-weekly dosing

Certain packaging, labeling, or manufacturer-specific formats may differ

Long-term effects, especially concerning chronic conditions like acid reflux, are thus not adequately captured

About 2% of American adults now take a GLP-1 drug to treat obesity, according to a report released by FAIR Health in May 2025

Health care providers should ensure they remain compliant with FDA regulations and appropriately guide their patients through this change

[10] [11] Working with a registered dietitian experienced in weight management can help ensure nutritional adequacy whilst achieving weight loss goals