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Patterson, E., Wall, R., Fitzgerald, G

Macedo B, Magalhaes J, Batista AR, Saraiva MJ

Chronic sleep deprivation or poor sleep quality impairs these restorative processes, potentially reducing glutathione synthesis capacity and increasing oxidative stress through various mechanisms including increased inflammatory signaling, impaired glucose metabolism, disrupted circadian rhythms affecting antioxidant enzyme expression, and increased psychological stress responses

Older Adults B12 deficiency affects approximately 6% of those under 60 but rises to around 20% of those over 60

Kim M, et al