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Stopping semaglutide typically leads to appetite rebound within weeks and weight regain over months, because the underlying metabolic factors that drove excess weight return once the medication is removed

DOI: 10.1056/NEJMoa1616011 [Google Scholar] Kaul S

Thus, the GLP-1 WT albiglutide-mimic demonstrated in vivo functionality and glucose-lowering properties on par with those of Tanzeum

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Individuals with higher baseline HbA1c levels or greater insulin resistance may experience more dramatic improvements in blood glucose control, though it may take longer to achieve target levels

Avoid use during pregnancy unless prescribed