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Notably, disruption of protein homeostasis is not only a direct consequence of heat stress but also an important trigger for the activation of the HSP system (Rutledge et al., 2022
Moreover, oxidative stress can enhance the expression of adhesion molecules and proteases, facilitating cancer cell detachment, invasion into surrounding tissues, and entry into the bloodstream [120]
[1] Aspartyl residues in peptides are known to be susceptible to isomerization, and DSIP contains both an Asp residue and adjacent Gly the sequence context most associated with that rearrangement
Dong, C
Mol Neurodegener 7:42
Exogenous GSH application with drought 26 and isoproturon toxicity 28 also reduces these stresses by increasing GSH content and GSH/GSSG ratio
