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"Brain and spine The Ehlers-Danlos Support UK"

(2016a)

Delivering it intravenously bypasses the gut entirely, putting the molecule directly into circulation

doi: 10.1038/s41419-020-03194-2 57 XuTDingWJiXAoXLiuYYuWet al

This means that if you take more than your body needs, the excess is generally excreted in your urine, which is why B12 is considered very safe, even at high doses