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10.1016/j.ejphar.2019.01.030 65 SeverM.KlicekR.RadicB.BrcicL.ZoricicI.DrmicD.et al (2009)
Sekhar, R.V., McKay, S.V., Patel, S.G., Guthikonda, A.P., Reddy, V.T., Balasubramanyam, A
By modulating electrostatic interactions between charged peptide drugs and the polymer matrix, these hydrogels enable sustained and steady drug elution over extended periods, ranging from days to weeks, significantly reducing dosing frequency from daily to weekly or even monthly intervals [46]
PMID 30790565
This review summarizes the role of epigenetics in depression, focusing on DNA methylation, RNA modification, and histone modification (Fig
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