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KEGG suggested that the PI3K-Akt signaling pathway and the cell cycle pathway were significantly enriched in the differential genes, and that RRM2 might affect thyroid cancer cell proliferation and survival

However, N-acetylcysteine (NAC), a glutathione precursor, has the strongest clinical evidence and is used in NHS hospitals, making it a more reliable option despite not being a direct glutathione supplement

PMID 29889360

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Linked to pathways involved in energy balance at the cellular level