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Phase I: modification, phase II: conjugation, and phase III: excretion
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Standard protocols suggest 0.25 to 0.5 mg daily via subcutaneous injection for general healing support
These findings reinforce the role of GLP-1RAs, and semaglutide in particular, as an important therapeutic option for patients with type 2 diabetes and established cardiovascular disease, supporting their inclusion in evidence-based guideline recommendations
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