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Todo ello hace que existan diferencias entre ellos en cuanto a su potencia en reduccin de HbA1c, glucemia basal o la reduccin ponderal, entre otros factores, que deben considerarse al elegir frmacos de esta familia78,83,84
Clinical data highlights a clear difference in efficacy between the two
32 DSM-V (2013)
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For example, lung cancer cell-lines show different sensitivities to doxorubicin in the form of GSH depletion, with A549 and GLC 4 210(S) cells experiencing approximately 50% and 64% GSH depletion after a 12 hour exposure to 70 nM and 5 nM (per million cells) respectively 37
