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Potency of these variant fusions ranged over several orders of magnitude and some of the mutations at positions G2, L26 and I23 resulted in partial agonism (Fig

These three use cases reflect different biological contexts and different expected time horizons for response

Subsequently, ribosomal protein S6 (RPS6), the subunit of eukaryotic translation initiation factor 2 (eIF2), and eukaryotic translation elongation factor 2 (eEF2) undergo phosphorylation (Dong et al., 2018)