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Researchers and clinicians using it do so based on extrapolation from animal data and accumulating clinical experience rather than proven efficacy in humans
It is supplied exclusively for laboratory research involving qualified investigators studying metabolic biology, adipose tissue physiology, and enzyme signaling pathways
Most often orally, as a daily capsule one of its practical advantages
Treatment typically involves vitamin B12 supplementation, either through oral supplements or injections, depending on the severity of the deficiency and underlying causes.
PMID: 28121423 | doi:10.1021/acs.biochem.6b01215 Akar S et al
That is why tests like methylmalonic acid (4) tend to be much more accurate than serum B12 levels
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