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(More information) While observational studies have associated higher intakes of vitamin E with lower risks of dementia and Alzheimers disease, clinical studies have not shown a benefit of -tocopherol supplementation in the primary prevention of dementia

In 2022, Lu et al

In the PIVENS trial, vitamin E (-tocopherol) was found to reduce MDA levels and improve histological features in MASLD patients [141]

Rare drop in zinc levels with long-term use (due to antioxidant effects)

E.KernJ

PPIs might serve as a latent trigger for hapten-reactive T cells, which are then further stimulated by ICIs, causing a loss of tolerance [194]