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rolled out top-line phase III data from Triumph-1 showing that all doses of retatrutide met primary and key secondary endpoints for obesity, with participants losing on average between 19% and 28.3% of body weight and significantly improving their cardiovascular risk factors
Moreover, these findings hold significant implications for developing novel therapeutic strategies targeting the NRF2/ARE pathway as well as other antioxidative pathways such as p53 and HIF
This suggests the eventual prescribing approach may involve reaching a target weight and then adjusting the dose downward to maintain it, rather than stopping treatment entirely
Nutrients, 12 (7), 1955
Biochemistry of postmortem brains in parkinsons disease: historical overview and future prospects
