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Older adults, for example, often experience conditions that affect their ability to absorb nutrients

Moreover, oral BPC-157 has a low bioavailability and does not usually have a direct effect on tissues outside the gastrointestinal tract (e.g., tendons and nerves)

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The introduction of the oral version of semaglutide in 2019 marked a significant milestone, offering more convenient administration options

Although clinical trials specifically for MASH have not yet been conducted, preclinical studies confirm significant regulatory effects on hepatic metabolism, providing a novel strategy for targeted MASH therapy and supporting future translational research