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A B12 shot is not a stimulant, so you should not expect a sudden caffeine-like jolt minutes after your appointment

The scale may move modestly

Some physicians limit B12 shots only to those with documented deficiencies or absorption issues to prevent unnecessary treatment where dietary B12 is sufficient

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Hypokalemia: Rapid treatment of severe anaemia with vitamin B12 could cause low potassium levels (hypokalemia), necessitating monitoring

However, for those experiencing low libido due to fatigue or mood , B12 could help reset the foundation of how you feel