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Without being limited to normal diet, hypercaloric contents (high fat and high fructose) in an MCD diet more easily cause metabolic changes characteristic of obesity, which may promote the occurrence of hepatic steatosis

After 21 off-drug days, long-lasting alterations in the glia, microvessel architecture and to cognitive tasks were evaluated by GFAP, CD11b and von Willebrand immunostaining and by short-term and working memory assessment

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This then shuts down a protein called ROCK1

For the 3 flanking region a PCR with oligos ogliH2 and ogliH3 was performed