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The studys primary endpoint was the reduction in participant hemoglobin A1c over the course of 26 weeks (results shown in chart above)
Regulatory status and translational considerations No GLP-1 receptor agonist is approved for any neurological or psychiatric indication
Inhibition of mTORC1 pathway by rapamycin was without effect on the ISR, suggesting that mTORC1 signaling does not contribute to the ISR in this setting
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This study was designed to systematically investigate the cartilage-protective effects of AOD9604, both alone and in combination with HA, using a well-established collagenase-induced OA rabbit model
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