NICE NG28 recommends DPP-4 inhibitors as add-on therapy in type 2 diabetes management, or as an alternative first-line option if metformin is contraindicated or not tolerated
One study on patients with major depressive disorder compared patients with hyperphagic versus hypophagic symptoms with healthy controls, finding differential effects of ghrelin depending on somatic symptom profile (Cerit et al., 2019)
Clinical Resources from Pharmacists Letter, Pharmacy Technicians Letter, and Prescriber Insights : Article: Be Ready for the New Oral GLP-1 Agonist Orforglipron Chart: GLP-1 and GIP/GLP-1 Receptor Agonist Interactive Comparison Chart Chart: Comparison of Weight Loss Products Dont miss out
Patients with pre-existing diabetic retinopathy should be monitored closely, especially if on insulin, due to the risk of transient worsening with rapid glycaemic improvement
The immune system shifts dramatically toward Th2 dominance, flooding the skin with interleukin-4 (IL-4), interleukin-13 (IL-13), and interleukin-31 (IL-31)
In fact, the drug has a boxed warning for this risk