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According to FDA-approved labeling and clinical trial data, the following side effects occur most commonly: Gastrointestinal Effects: Nausea (affecting 1544% of patients, with higher rates at Wegovy doses) [3] [4] Diarrhea (reported in 830% of patients) Vomiting (524% incidence) Constipation (occurring in 324% of patients) Abdominal pain (520% of patients) These gastrointestinal symptoms typically emerge during dose escalation and often diminish with continued therapy as physiological adaptation occurs
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