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The investigators will randomly assign 50 participants to receive semaglutide (titrated to 7 milligrams (mg) per day) or matched placebo for 8 weeks

Research approved by the FDA showed semaglutide caused an average of about 15 percent weight loss over 68 weeks

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Metformin combined with thiazolidinediones were particularly effective in promoting the recovery of menstruation in PCOS patients