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Despite this trend, doctors still struggle to offer solid guidance on using these drugs during pregnancy because reliable human safety data remains scarce

These challenges highlight why combining lifestyle changes with other methods might be more effective for some individuals

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Low-dose TMAO treatment can reduce plasma N-terminal pro-B-type natriuretic peptide and vasopressin, left ventricular end-diastolic pressure, and cardiac fibrosis in pressure-overloaded hearts in hypertensive rats (22)