Percentage BMI change over 12 months The overall median percentage reduction in BMI was 2.5% after 0-3 months, 4.5% after 3-6 months, 6.4% after 6-9 months, and 6.3% after 9-12 months ( Figure 2 )
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The variance of half a unit at these concentrations is clinically insignificant, amounting to roughly 0.017 mg difference
GLP-1 stimulation in the microbiome Human intestinal cells show Akkermansias effect on GLP-1 production Akkermansia secretes p9 protein which stimulates GLP-1 production Clostridium butyricum increases GLP-1* Dose-dependent increase of GLP-1 by Clostridium butyricum in a cell-based assay *Based on internal Pendulum R&D data Breakthrough clinical research Were continually pushing the boundaries in scientific research, and were excited to conduct a human clinical trial on GLP-1 and the gut microbiome