The author also thank collaborator who have been important for the studies, in particular Suad Efendic and late Mark Gutniak (Stockholm, Sweden), Giovanni Pacini (Padua, Italy), James Foley and Anja Schweizer (Novartis), and Richard Carr (Merck)
A systematic review of these data is available [17]
One of these has a single encouraging trial behind it, one helps only the small number of people who are genuinely deficient, and the rest of the shelf is selling hope by monthly subscription
Endoplasmic reticulum (ER) stress, which contributes to protein misfolding and cell stress responses (10)
That single difference explains more than anything else youll read about these drugs, and Ill come back to it properly
There is therefore an unmet clinical need for therapeutics which effectively reduce ICP without further impacting on cognitive function