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The effect these drugs had on weight did not long go unnoticed, however, as losing fat can help people with type 2 diabetes control their blood sugars better, and even make the condition go into remission
The paradox resolves when you stop looking for a single answer
While GPR119 activation stimulates GLP-1 secretion in primary duodenal cultures, activation is not absolutely required for GLP-1 secretion as shown by L cell specific knockout (Psichas et al., 2017)
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Semaglutide, the active ingredient in the anti-diabetes drug Ozempic and anti-obesity medication Wegovy, can help people lose weight and reduce their risk of serious heart problems
In fact, failure to understand this factor can really mess up your experience
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