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The reason for this wait, also called a deferral period, is because CSL is mandated to comply with various global regulatory requirements

Complete rest leads to deconditioning and does little to stimulate active repair

A study in female patients with obesity who were prescribed a 925 kcal diet for 16 weeks followed by a 12001500 kcal diet for 32 weeks showed 11% weight loss in the first 2 months with reductions in triglycerides and total cholesterol by 22.7% and 15.7% respectively [29]

And I cannot overstate the slippery slope GLP-1s create for those with a history of disordered eating or body image struggles (and lets be honest thats a lot of the people who feel drawn to these medications)

Jul., Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis, Nature , vol