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We identified a reacting pair that led to a thioether-linked dimer with submicromolar potency in cell-based assays
We further demonstrated that TgSNF2a and TgSNF2b interact with each other and core components of SWI/SNF complex, and coordinately activate the organelle-related genes specifically expressed during tachyzoite stages
By utilizing a sustained-release formulation, it overcomes the historical challenges of oral bioavailability, providing a steady, reliable defense against the relentless oxidative stress that characterizes post-viral syndromes
tissue microarray-based immunohistochemical study
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