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It plays an important role in cellular repair and energy metabolism
In the landmark SURPASS-2 clinical trial, Mounjaro achieved A1C reductions of up to 2.3% versus 1.9% for injectable semaglutide, while producing approximately 2.5 times greater weight loss (12.4 kg vs 6.2 kg)
Edwards CM, Todd JF, Mahmoudi M, Wang Z, Wang RM, Ghatei MA et al
Because of this, it has become a major target in drug discovery for treating type 2 diabetes and obesity
Supplement manufacturers do not
In large-scale longer-term cardiovascular outcomes trials [47, 48, 84], long-term DPP-4 inhibition was associated with no change or a small decline in glomerular function that persisted during the entire duration of follow-up (up to 4 years)
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