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Healthy eating and exercise are critical parts of losing weight and keeping it off
PMID: 26 CorrellCUManuPOlshanskiyVNapolitanoBKaneJMMalhotraAK
Week 29 onward: Retatrutide 8-12 mg weekly + Cagrilintide 2.0-2.4 mg weekly
The microdosing philosophy recognizes that sustainable weight management requires patient comfort and confidence throughout extended treatment periods
It is driven by excessive energy expenditure, catabolism, and inflammation linked to increased proinflammatory cytokines, enhanced proteasomic muscle degradation, and significant lipolysis [ 9 ]
The dose is typically started low and gradually increased to the target dose as tolerated
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