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The FLOW trial demonstrated clear kidney and cardiovascular protection with GLP-1 receptor agonist (GLP-1RA) treatment in individuals with type 2 diabetes and chronic kidney disease (CKD)

Although some extol the drugs health benefits, most focus on economics, including the drugs high cost, the growing reluctance of private and public insurance plans to cover the expense and the resulting affordability crisis for patients

it does not predict response to retatrutide or recommend any specific medication

Because dehydration makes nausea and vomiting worse

There's no direct evidence from canine studies, but the rodent findings create a biological rationale for further investigation in larger animal models

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