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Key points to consider when interpreting the evidence: Most studies are short-term , typically lasting fewer than 12 weeks, making it difficult to assess long-term efficacy or safety Results appear more pronounced in older adults or individuals with obesity, compared to younger, healthy populations L-carnitine alone, without dietary or lifestyle changes , is unlikely to produce clinically meaningful weight loss Neither NICE nor the NHS recommends L-carnitine supplementation as part of any weight management pathway

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How GLP-1 Agonists Work in the Body GLP-1 drugs mimic a natural hormone called glucagon-like peptide-1, which is a vital part of blood sugar and appetite regulation

Slominski, A.T

For example, obesity is associated with a higher risk of developing several cancers, including kidney and liver cancer