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Interestingly, GI adverse events and GLP-1 RA discontinuations were more common in participants not treated with metformin, which may represent increased susceptibility of this group to gut-related adverse events, resulting in intolerance to metformin previously as well as to GLP-1 RAs in the trials

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This method is often used to treat or prevent vitamin B12 deficiency, which can lead to serious health problems if left untreated

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Patients should not stop taking prescribed medication without first consulting a healthcare provider, as abrupt changes can pose additional risks

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