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doi:10.1111/obr.12436 Chee, C et al

As expected, with time or with increase of H 2 O 2 concentration, the protein levels of progerin, p53, and p21 in primary rat hepatocytes showed a concentration-dependent and a time-dependent upregulation of progerin expression and activation of the p53/p21 pathway, as a result of oxidative stress (Supplementary Fig

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