Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)
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They also occur from exposure to environmental toxins and pollutants, and from long periods of ongoing stress
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In addition, significant transcriptional induction of several PR genes as well as differential changes in multiple GST transcripts were observed (Sana et al., 2010)
Furthermore, no phase transfer was observed at extremely basic (11.5) or acidic (1.5 and 3) pH values at which either the amine groups in DDA or the carboxylic acid groups in GSH molecules are not charged, respectively (Fig