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In pernicious anaemia, the immune system mistakenly attacks the gastric parietal cells that produce intrinsic factor, leading to B12 deficiency over time

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272 Exendin-4 also promoted apoptotic resistance and improved viability in NSC19 neuronal cells (a mouse cell line) during oxidative stress

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It inhibits tyrosinase (the key enzyme that makes dark melanin) and shifts pigment synthesis toward lighter pheomelanin