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10.1016/j.bbr.2021.113142 203
Full text: Pizzorno J
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Besides, researchers have synthesized mitochondria-targeted liposome nanoparticles (MLipRIR NPs), which could be activated by ultrasound and released R162 that disrupted the glutaminolysis pathway in mitochondria and down-regulates glutathione peroxidase (GPx) enzyme expression
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In laboratory and pre-clinical research settings, native GLP-1 serves as the primary pharmacological reference standard for studying GLP-1 receptor binding, activation, and downstream signalling as well as the broader incretin axis and its connections to pancreatic -cell biology, appetite regulation, gastric motility, cardiovascular function, and neuroprotection
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