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At $146-$258/month for 6-month plans (for semaglutide and tirzepatide respectively), Yucca Health's pricing is competitive with other major compounded GLP-1 telehealth platforms, most of which range from $150-$400/month depending on medication and commitment level

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The FDA label also includes important warnings and precautions, including risk of thyroid C-cell tumors observed in rodents, contraindication in patients with a personal or family history of medullary thyroid carcinoma or MEN2, pancreatitis concerns, gallbladder disease, hypoglycemia risk when used with insulin or insulin secretagogues, hypersensitivity reactions, kidney injury from dehydration, diabetic retinopathy complications in some patients with diabetes, and suicidal behavior or ideation monitoring

When the sub-study began, all of the participants had blood pressure levels that were less than 140/90 mm Hg, and if they used blood pressure medications, they were required to have been taking their blood pressure medications for at least three months