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Compounded tirzepatide is a once-weekly GLP-1 and GIP medication designed to support weight loss and improve metabolic health

Wester A, Shang Y, Toresson Grip E, Matthews AA, Hagstrm H

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However, it's important to recognize a specific risk: some GLP-1s are associated with a higher proportion of lean mass loss, a particularly significant concern for menopausal women already facing muscle and bone density challenges

Similarly, glucagon-like peptide-1 (GLP-1) analogs bind to GLP-1 receptors, stimulating insulin release in a glucose-dependent manner while also slowing gastric emptying and promoting satiety

The UK SmPC includes a specific warning about this risk