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Vitamin B12 deficiency Having trouble absorbing vitamin B12 from food, lacking intrinsic factors (for example, as a result of pernicious anaemia), having gastrointestinal surgery, taking certain medications for an extended period of time (such as metformin or proton pump inhibitors), and nutritional deficiencies are all causes of vitamin B12 deficiency

Unopened vials generally retain stability for up to two years

The healing parameters were tested on different days following euthanization of the animals

Presented for research literature review only Leonel C et al

(2025) Pharmaceuticals (Basel) Storage, Handling & Stability Guidelines Use the applicable lot/source record for storage of unopened material

Some medications can also affect vitamin B12 absorption in the gut