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The primary outcome was a composite of the first occurrence of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke
Among the newly developed compounds, 49, 50, 51, and 52 (Figure 35) were found to be the most effective inhibitors of PGE2 and NO production induced by LPS
Results typically become visible within a few weeks, with maintenance sessions recommended for long-term benefits
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