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Short answer: we don't know, because compounded medications aren't individually tested for safety, quality and efficacy by the TGA
The details: In March 2024, Altimmune announced the results of MOMENTUM, a phase 2 trial in which people received weekly injections of pemvidutide as an obesity treatment
No medical organization currently recommends combining phentermine and semaglutide due to cardiovascular risks from phentermine's stimulant effect combined with semaglutide's hemodynamic actions
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A 2023 observational study found that patients on GLP-1 therapy maintained 60% of their weight loss two years after treatment initiation, whereas phentermine users retained less than 20% of losses after stopping the drug
Clinical practice guidelines
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