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Research in Hepatology (2019) demonstrated that genetic variants of ABCB1 and ABCC2 transporters significantly affect elimination rates
The non-DAC form clears faster, which makes it gentler but requires more frequent injections
In LPS-induced depression, inflammatory challenge directly induces mitochondrial abnormalities, including disrupted morphology, reduced ATP production, ROS accumulation, and suppression of mitochondrial biogenesis and mitophagy across multiple brain regions
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