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Together, these findings suggest that X(PC) triggers a caspase-1-dependent lytic cascade, but that this pathway is only partially sensitive to QVD inhibition likely due to the threshold-like nature of pyroptotic signaling, and that off-target cleavage of proteins such as the substrates uncovered during profiling contributes to this complex, PANoptotic-like cell death

10.1007/s42000-019-00112-w Hormones 193 SolovyevN.BertheleA.MichalkeB

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J., Thomas, C

Effects of oral L-carnitine supplementation on lipid profile, anemia, and quality of life in chronic renal disease patients under hemodialysis: A randomized, double-blinded, placebo-controlled trial